SMAD9
Associated conditions:
- Pulmonary arterial hypertension
SMAD9 relays BMP growth signals inside cells, a pathway that keeps the small arteries of the lungs healthy. Genetic changes in this gene are associated with an autosomal dominant contribution to pulmonary arterial hypertension, in which these vessels narrow and strain the heart, often beginning in childhood. Knowing your genetic status enables earlier diagnosis and treatment before serious damage occurs.
Conditions linked to SMAD9
Pulmonary arterial hypertension
Pulmonary arterial hypertension is high blood pressure in the arteries of the lungs, which strains the right side of the heart and causes breathlessness. Inherited forms exist, and specialist treatment can slow it, so early diagnosis matters.
