Skip to content

HOXB13

Associated conditions:

  • Prostate cancer

HOXB13 is a master-switch gene that controls how prostate tissue develops and responds to male hormones. Genetic changes in this gene are associated with an increased lifetime risk of prostate cancer, especially early-onset and familial forms. Knowing your genetic status enables earlier and more regular PSA testing.

Conditions linked to HOXB13

Prostate cancer

Prostate cancer develops in the prostate gland. Certain inherited variants raise lifetime risk and the chance of a more aggressive form, so carriers are often offered earlier and more regular PSA testing.