Skip to content

CDKN1B

Associated conditions:

  • Endocrine benign tumours

CDKN1B makes p27, a protein that puts the brakes on cell division. Genetic changes in this gene are associated with an autosomal dominant condition called MEN4, a syndrome of tumours in hormone glands such as the parathyroid and pituitary. Knowing your genetic status enables periodic hormone and imaging checks to catch these tumours early.