HNF1B
Associated conditions:
- MODY5
HNF1B is a transcription factor that helps direct development of the kidneys, pancreas, liver and reproductive tract. Genetic changes in this gene are associated with an autosomal dominant, young-onset form of diabetes called MODY5, usually combined with kidney cysts and reduced kidney function. Knowing your genetic status enables tailored diabetes treatment and kidney monitoring.
Tests that include HNF1B:
Conditions linked to HNF1B
MODY5
MODY5 is a form of maturity-onset diabetes of the young caused by HNF1B variants, often alongside kidney cysts or other kidney and genital-tract differences. Diagnosis guides both diabetes and kidney care and is relevant for family members.
