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HNF1A

Associated conditions:

  • MODY3

HNF1A is a transcription factor that switches on genes the pancreas needs to release insulin properly. Genetic changes in this gene are associated with an autosomal dominant, young-onset inherited diabetes called MODY3, often misread as type 1 or type 2 diabetes. Knowing your genetic status enables the right diagnosis, since it usually responds well to low-dose sulfonylurea tablets rather than insulin.

Conditions linked to HNF1A

MODY3

MODY is an inherited form of diabetes that appears in younger people and is caused by a single gene. Identifying it matters because some types are best treated with specific tablets rather than insulin, and it has implications for relatives.