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BCHE

Associated conditions:

  • Butyrylcholinesterase deficiency

BCHE makes an enzyme in the blood that breaks down certain muscle-relaxant drugs used during anaesthesia. Genetic changes in this gene are associated with an autosomal recessive deficiency in which these drugs clear very slowly, so the paralysis they cause and the need for breathing support can last far longer than expected. Knowing your genetic status enables the anaesthetic team to plan safely.

Conditions linked to BCHE

Butyrylcholinesterase deficiency

Butyrylcholinesterase deficiency changes how the body breaks down certain muscle-relaxant anaesthetics used in surgery. It does not affect everyday health, but it can prolong the effect of these drugs, so telling your anaesthetist before any operation is the key precaution.