Your DNA is analysed in a CLIA and CAP certified laboratory for variations in 61 genes associated with some of the most common types of cancer.
Some of the genes on the test include —
Breast, ovarian, pancreatic, prostate cancer and melanoma.
Lynch Syndrome: bowel, ovarian and uterine cancer.
Breast, colorectal, endocrine, ovarian, and prostate cancer.
Gene | Conditions |
---|---|
APC | Colorectal, endocrine, gastric, nervous system/brain, and pancreatic cancer, sarcoma |
ATM | Breast, pancreatic, and prostate cancer |
AXIN2 | Colorectal cancer |
BAP1 | Renal/urinary tract cancer, melanoma |
BARD1 | Breast cancer |
BMPR1A | Colorectal, gastric, and pancreatic cancer |
BRCA1 | Breast, gynecologic, pancreatic, and prostate cancer |
BRCA2 | Breast, gynecologic, pancreatic, and prostate cancer, melanoma |
BRIP1 | Breast and gynecologic cancer |
CDC73 | Endocrine and renal/urinary tract cancer |
CDH1 | Breast, colorectal, and gastric cancer |
CDK4 | Melanoma |
CDKN2A | Nervous system/brain and pancreatic cancer, melanoma |
CHEK2 | Breast, colorectal, endocrine, gynecologic, and prostate cancer |
DICER1 | Endocrine, gynecologic, nervous system/brain, and renal/urinary tract cancer, sarcoma |
EPCAM | Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer |
FH | Renal/urinary tract cancer, sarcoma |
FLCN | Renal/urinary tract cancer |
GREM1 | Colorectal cancer |
HOXB13 | Prostate cancer |
KIT | Gastric cancer, sarcoma |
MAX | Endocrine cancer |
MEN1 | Endocrine, nervous system/brain, and pancreatic cancer |
MET | Renal/urinary tract cancer |
MITF | Melanoma |
MLH1 | Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer |
MSH2 | Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer |
MSH3 | Colorectal cancer, includes reporting of carrier status |
MSH6 | Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer |
MUTYH | Colorectal cancer |
Gene | Conditions |
---|---|
NBN | Breast and prostate cancer |
NF1 | Breast, endocrine, gastric, and nervous system/brain cancer |
NF2 | Nervous system/brain cancer |
NTHL1 | Colorectal cancer, includes reporting of carrier status |
PALB2 | Breast and pancreatic cancer |
PDGFRA | Gastric cancer, sarcoma |
PMS2 | Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer |
POLD1 | Colorectal cancer |
POLE | Colorectal cancer |
PRKAR1A | Endocrine and nervous system/brain cancer, sarcoma |
PTCH1 | Nervous system/brain and skin cancer, sarcoma |
PTEN | Breast, colorectal, endocrine, gynecologic, nervous system/brain and, renal/urinary tract cancer, melanoma |
RAD51C | Breast and gynecologic cancer |
RAD51D | Breast and gynecologic cancer |
RB1 | Melanoma, retinoblastoma, sarcoma |
RET | Endocrine cancer |
SDHA | Endocrine and gastric cancer, sarcoma |
SDHAF2 | Endocrine cancer |
SDHB | Endocrine, gastric, and renal/urinary tract cancer, sarcoma |
SDHC | Endocrine, gastric, and renal/urinary tract cancer, sarcoma |
SDHD | Endocrine, gastric, and renal/urinary tract cancer, sarcoma |
SMAD4 | Colorectal, gastric, and pancreatic cancer |
SMARCA4 | Gynecologic cancer |
SMARCB1 | Nervous system/brain and renal/urinary tract cancer |
STK11 | Breast, colorectal, gastric, gynecologic, and pancreatic cancer |
TMEM127 | Endocrine cancer |
TP53 | Breast, endocrine, gastrointestinal, genitourinary, gynecologic, hematologic, nervous system/brain, and skin cancer, sarcoma |
TSC1 | Nervous system/brain, pancreatic, and renal/urinary tract cancer |
TSC2 | Nervous system/brain, pancreatic, and renal/urinary tract cancer |
VHL | Endocrine, nervous system/brain, pancreatic, and renal/urinary tract cancer |
WT1 | Renal/urinary tract cancer |