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What do we test for?

Inherited gene variations that increase your risk of developing some of the most common types of cancer.

Your DNA is analysed in a CLIA and CAP certified laboratory for variations in 61 genes associated with some of the most common types of cancer.

Some of the genes on the test include —

Breast, ovarian, pancreatic, prostate cancer and melanoma.

Lynch Syndrome: bowel, ovarian and uterine cancer.

Breast, colorectal, endocrine, ovarian, and prostate cancer.

Some additional details for clinicians —

Our honesty policy

The (not so) fine print.

What this test CAN DO:
What this test CANNOT DO:

List of genes screened and associated cancer types —

Gene Conditions
APCColorectal, endocrine, gastric, nervous system/brain, and pancreatic cancer, sarcoma
ATMBreast, pancreatic, and prostate cancer
AXIN2Colorectal cancer
BAP1Renal/urinary tract cancer, melanoma
BARD1Breast cancer
BMPR1AColorectal, gastric, and pancreatic cancer
BRCA1Breast, gynecologic, pancreatic, and prostate cancer
BRCA2Breast, gynecologic, pancreatic, and prostate cancer, melanoma
BRIP1Breast and gynecologic cancer
CDC73Endocrine and renal/urinary tract cancer
CDH1Breast, colorectal, and gastric cancer
CDK4Melanoma
CDKN2ANervous system/brain and pancreatic cancer, melanoma
CHEK2Breast, colorectal, endocrine, gynecologic, and prostate cancer
DICER1Endocrine, gynecologic, nervous system/brain, and renal/urinary tract cancer, sarcoma
EPCAMColorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer
FHRenal/urinary tract cancer, sarcoma
FLCNRenal/urinary tract cancer
GREM1Colorectal cancer
HOXB13Prostate cancer
KITGastric cancer, sarcoma
MAXEndocrine cancer
MEN1Endocrine, nervous system/brain, and pancreatic cancer
METRenal/urinary tract cancer
MITFMelanoma
MLH1Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer
MSH2Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer
MSH3Colorectal cancer, includes reporting of carrier status
MSH6Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer
MUTYHColorectal cancer
Gene Conditions
NBNBreast and prostate cancer
NF1Breast, endocrine, gastric, and nervous system/brain cancer
NF2Nervous system/brain cancer
NTHL1Colorectal cancer, includes reporting of carrier status
PALB2Breast and pancreatic cancer
PDGFRAGastric cancer, sarcoma
PMS2Colorectal, gastric, gynecologic, nervous system/ brain, pancreatic, prostate, and renal/urinary tract cancer
POLD1Colorectal cancer
POLEColorectal cancer
PRKAR1AEndocrine and nervous system/brain cancer, sarcoma
PTCH1Nervous system/brain and skin cancer, sarcoma
PTENBreast, colorectal, endocrine, gynecologic, nervous system/brain and, renal/urinary tract cancer, melanoma
RAD51CBreast and gynecologic cancer
RAD51DBreast and gynecologic cancer
RB1Melanoma, retinoblastoma, sarcoma
RETEndocrine cancer
SDHAEndocrine and gastric cancer, sarcoma
SDHAF2Endocrine cancer
SDHBEndocrine, gastric, and renal/urinary tract cancer, sarcoma
SDHCEndocrine, gastric, and renal/urinary tract cancer, sarcoma
SDHDEndocrine, gastric, and renal/urinary tract cancer, sarcoma
SMAD4Colorectal, gastric, and pancreatic cancer
SMARCA4Gynecologic cancer
SMARCB1Nervous system/brain and renal/urinary tract cancer
STK11Breast, colorectal, gastric, gynecologic, and pancreatic cancer
TMEM127Endocrine cancer
TP53Breast, endocrine, gastrointestinal, genitourinary, gynecologic, hematologic, nervous system/brain, and skin cancer, sarcoma
TSC1Nervous system/brain, pancreatic, and renal/urinary tract cancer
TSC2Nervous system/brain, pancreatic, and renal/urinary tract cancer
VHLEndocrine, nervous system/brain, pancreatic, and renal/urinary tract cancer
WT1Renal/urinary tract cancer

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Frequently Asked Questions

Genetic counsellors guide people in making important decisions around how genetics influences their health. They are not doctors, but are genetic specialists that are trained to identify, explore and explain genetic risk. They can help you be practically and emotionally prepared to make empowered choices that feel right for you.

At no additional cost, connect with your Eugene genetic counsellor to discuss your test results. They can help you understand your results, answer any questions and help you learn more about what your results mean for you.

No. Genetics is only one part of the cancer risk puzzle. Having a gene variant in one of the genes included on our test will increase your chance of developing cancer, but not everyone who has a gene variation will get cancer in their lifetime.

There are many other factors that contribute to your risk, including environmental factors like exposure to the sun and lifestyle factors like smoking and exercise. If a gene variant is identified on our test, your results will include information about the specific gene variation you carry and how it influences your cancer risk so you can better understand your lifetime chance of developing that specific type cancer.

In some cases this test could impact your ability to get life or income protection insurance.

Not impacted—

  • Your ability to get health insurance
  • Your existing life and/or income protection cover. However, if you want to take out cover or change your existing policy, this test may have an impact.
  • Life and other insurances through super that are group policies and don’t take into account personal medical history.
  • If your result doesn’t identify a gene variant then your insurance shouldn’t be impacted.

Could have an impact —

  • If you want to take out cover or change your existing policy, this test may have an impact.
  • On policies that do consider your medical history, like underwritten policies above certain coverage amounts (currently $500,000 for life insurance). If a gene variation that increases your risk of cancer is identified before you have taken out cover, you may be denied cover, or have to pay a higher premium or have policy exclusions.

For more information about how life and other insurance products may be impacted by genetic testing, visit the Financial Services Council or the Center for Genetics Education website.

Your result will help you and your doctor determine any action strategies for prevention and early detection that might be appropriate for you.

You can learn more about that here.

Eugene’s proactive cancer risk test includes a personal clinical report that will have details about your results, that you can share with your doctor. The clinical report is available for you when you receive your results.

You can also speak with a Eugene genetic counsellor at no additional charge. Genetic counsellors can help you understand your results, consider next steps, and discuss how to share information with doctors and family.

From the moment we receive your saliva sample, the turnaround time to get your results are 3 to 6 weeks.

Absolutely! Each test comes with a post test genetic counselling session. Your Eugene genetic counsellors are all trained and have practiced across a number of specialties in addition to carrier screening and together with our consultant geneticists and widespread network of healthcare professionals, we make sure you’re always connected and supported.

As a healthcare company, we comply with the most stringent local and inernational privacy and security regulations. We take incredible care to use technical, process and physical safeguards to secure your personal information and protect it against misuse, loss or alteration.

Finally, Eugene doesn’t share any your data with anyone but you and (with your express permission) your doctor.

Yes. Even if you don’t have a family history you could still have a genetic risk that increases your own risk. Not everyone who carries an increased risk gene variant will develop cancer, so not every family will have a cancer history. So, while gene variations that increase cancer risk are rare, knowing whether or not there’s one in you or your family could be lifesaving.

Your saliva sample is destroyed after 30 days. In unusual cases when testing takes longer than 30 days, the specimen will be retained until the report is delivered.

More questions?

We’ve pulled together other things we think might help in this FAQ – if you have any more questions for us, just get in touch!